Restrictive cardiomyopathy caused by chloroquine.
نویسندگان
چکیده
A 59 year old white woman who had been treated with chloroquine phosphate for 25 years presented with signs of congestive heart failure and was diagnosed as having restrictive cardiomyopathy by non-invasive methods. Electron microscopy of a biopsy specimen of skeletal muscle showed lesions compatible with chloroquine myopathy. The patient died five weeks after presentation. Electron microscopy of heart tissue showed similar lesions to those of the skeletal muscle.
منابع مشابه
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متن کاملCardiac toxicity secondary to long term treatment with chloroquine.
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متن کاملGenetic linkage of a novel autosomal dominant restrictive cardiomyopathy locus.
BACKGROUND In recent years, non-syndromic idiopathic cardiomyopathies have increasingly been characterised as autosomal dominant conditions caused by single gene mutations. Loci have been identified for hypertrophic and dilated cardiomyopathy, and in some cases the same loci are associated with restrictive cardiomyopathy (RCM). In a kindred with RCM that we previously reported, we ruled out the...
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عنوان ژورنال:
- British heart journal
دوره 69 5 شماره
صفحات -
تاریخ انتشار 1993